| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50098350 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1505006 (CHEMBL3595788) |
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| Ki | 4.7±n/a nM |
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| Citation |  Ibrahim, DA; Lasheen, DS; Zaky, MY; Ibrahim, AW; Vullo, D; Ceruso, M; Supuran, CT; Abou El Ella, DA Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. Bioorg Med Chem23:4989-99 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50098350 |
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| n/a |
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| Name | BDBM50098350 |
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| Synonyms: | CHEMBL3594422 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N8O4S6 |
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| Mol. Mass. | 656.867 |
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| SMILES | CS\C(=N/c1nc2ccc(cc2s1)S(N)(=O)=O)N1CCN(CC1)C(\SC)=N\c1nc2ccc(cc2s1)S(N)(=O)=O |
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| Structure | 
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