| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 4 |
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| Ligand | BDBM50100610 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1457660 (CHEMBL3368946) |
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| EC50 | 64000±n/a nM |
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| Citation |  Zachariassen, ZG; Thiele, S; Berg, EA; Rasmussen, P; Fossen, T; Rosenkilde, MM; Våbenø, J; Haug, BE Design, synthesis, and biological evaluation of scaffold-based tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4). Bioorg Med Chem22:4759-69 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 4 |
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| Name: | C-X-C chemokine receptor type 4 |
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| Synonyms: | C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4) | CD_antigen=CD184 | CXC-R4 | CXCR-4 | CXCR4 | CXCR4_HUMAN | FB22 | Fusin | HM89 | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor | NPYRL | SDF-1 receptor | Stromal cell-derived factor 1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39754.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P61073 |
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| Residue: | 352 |
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| Sequence: | MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVI
LVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNL
YSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEA
DDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKT
TVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPI
LYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
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| BDBM50100610 |
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| n/a |
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| Name | BDBM50100610 |
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| Synonyms: | CHEMBL3327376 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H38N8O2S |
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| Mol. Mass. | 538.708 |
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| SMILES | [H][C@@]12CN(CCc3ccc4ccccc4c3)C(=O)[C@H](CCCNC(N)=N)N1C(=O)[C@H](CCCNC(N)=N)CS2 |r| |
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| Structure | 
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