| Reaction Details |
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 | Report a problem with these data |
| Target | Subtilisin-like protease 1 |
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| Ligand | BDBM50100881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1456858 (CHEMBL3367591) |
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| IC50 | >50000±n/a nM |
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| Citation |  Kher, SS; Penzo, M; Fulle, S; Finn, PW; Blackman, MJ; Jirgensons, A Substrate derived peptidica-ketoamides as inhibitors of the malarial protease PfSUB1. Bioorg Med Chem Lett24:4486-9 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Subtilisin-like protease 1 |
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| Name: | Subtilisin-like protease 1 |
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| Synonyms: | SUB1 | SUB1_PLAFA | Subtilisin-like protease | Subtilisin-like serine protease | sub-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 77866.88 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_830092 |
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| Residue: | 690 |
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| Sequence: | MMLNKKVVALCTLTLHLFCIFLCLGKEVRSEENGKIQDDAKKIVSELRFLEKVEDVIEKS
NIGGNEVDADENSFNPDTEVPIEEIEEIKMRELKDVKEEKNKNDNHNNNNNNNNISSSSS
SSSNTFGEEKEEVSKKKKKLRLIVSENHATTPSFFQESLLEPDVLSFLESKGNLSNLKNI
NSMIIELKEDTTDDELISYIKILEEKGALIESDKLVSADNIDISGIKDAIRRGEENIDVN
DYKSMLEVENDAEDYDKMFGMFNESHAATSKRKRHSTNERGYDTFSSPSYKTYSKSDYLY
DDDNNNNNYYYSHSSNGHNSSSRNSSSSRSRPGKYHFNDEFRNLQWGLDLSRLDETQELI
NEHQVMSTRICVIDSGIDYNHPDLKDNIELNLKELHGRKGFDDDNNGIVDDIYGANFVNN
SGNPMDDNYHGTHVSGIISAIGNNNIGVVGVDVNSKLIICKALDEHKLGRLGDMFKCLDY
CISRNAHMINGSFSFDEYSGIFNSSVEYLQRKGILFFVSASNCSHPKSSTPDIRKCDLSI
NAKYPPILSTVYDNVISVANLKKNDNNNHYSLSINSFYSNKYCQLAAPGTNIYSTAPHNS
YRKLNGTSMAAPHVAAIASLIFSINPDLSYKKVIQILKDSIVYLPSLKNMVAWAGYADIN
KAVNLAIKSKKTYINSNISNKWKKKSRYLH
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| BDBM50100881 |
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| n/a |
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| Name | BDBM50100881 |
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| Synonyms: | CHEMBL3325863 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H39N5O9 |
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| Mol. Mass. | 529.5839 |
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| SMILES | CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NC(C)(C)C(=O)NC(C)C(=O)C(=O)NCCC(O)=O |r| |
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| Structure | 
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