| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-glucuronosyltransferase 2B7 |
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| Ligand | BDBM50103451 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1462522 (CHEMBL3399067) |
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| IC50 | >300000±n/a nM |
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| Citation |  Nair, V; Okello, MO; Mangu, NK; Seo, BI; Gund, MG A novel molecule with notable activity against multi-drug resistant tuberculosis. Bioorg Med Chem Lett25:1269-73 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-glucuronosyltransferase 2B7 |
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| Name: | UDP-glucuronosyltransferase 2B7 |
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| Synonyms: | 2.4.1.17 | 3,4-catechol estrogen-specific UDPGT | UD2B7_HUMAN | UDP-glucuronosyltransferase 2B7 | UDP-glucuronosyltransferase 2B9 | UDPGT 2B7 | UDPGT 2B9 | UDPGTh-2 | UGT2B7 | UGTB2B9 | Uridine-5'-diphosphoglucuronosyltransferase 2B7 |
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| Type: | Enzyme |
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| Mol. Mass.: | 60705.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16662 |
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| Residue: | 529 |
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| Sequence: | MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSA
SILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFG
DITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTF
EKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVL
GRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSG
ENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQN
DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTM
SSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAA
HDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND
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| BDBM50103451 |
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| n/a |
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| Name | BDBM50103451 |
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| Synonyms: | CHEMBL3398252 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H31F3N4O4 |
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| Mol. Mass. | 652.6616 |
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| SMILES | O\C(=C/C(=O)c1cc(Cc2cc(F)cc(F)c2)cn(Cc2ccccc2F)c1=O)C(=O)N1CCN(CC1)c1ccc(cc1)-n1cccc1 |
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| Structure | 
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