| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 3 |
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| Ligand | BDBM50110466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1510034 (CHEMBL3606126) |
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| Ki | 24±n/a nM |
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| Citation |  Lai, Z; He, S; Sherer, EC; Wu, Z; Yu, Y; Ball, R; Hong, Q; Yang, DX; Guo, L; Li, D; Tuang, Q; Chicchi, GG; Trusca, D; Tsao, KL; Zhou, YP; Howard, AD; Nargund, RP; Hagmann, WK Discovery of substituted (4-phenyl-1H-imidazol-2-yl)methanamine as potent somatostatin receptor 3 agonists. Bioorg Med Chem Lett25:3520-5 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 3 |
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| Name: | Somatostatin receptor type 3 |
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| Synonyms: | SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3) |
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| Type: | Protein |
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| Mol. Mass.: | 45855.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32745 |
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| Residue: | 418 |
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| Sequence: | MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL
GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM
AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV
FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV
WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA
LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE
SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
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| BDBM50110466 |
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| n/a |
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| Name | BDBM50110466 |
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| Synonyms: | CHEMBL3605794 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28N4O |
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| Mol. Mass. | 400.516 |
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| SMILES | COc1cccc2c(CNC3(CCCC3)c3nc(c[nH]3)-c3ccc(C)cc3)c[nH]c12 |
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| Structure | 
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