| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50117677 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1515207 (CHEMBL3614554) |
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| Ki | 3.1±n/a nM |
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| Citation |  Buemi, MR; De Luca, L; Ferro, S; Bruno, E; Ceruso, M; Supuran, CT; Pospí?ilová, K; Brynda, J; Rezácová, P; Gitto, R Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. Eur J Med Chem102:223-32 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50117677 |
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| n/a |
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| Name | BDBM50117677 |
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| Synonyms: | CHEMBL3613778 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18N2O4S |
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| Mol. Mass. | 346.401 |
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| SMILES | COc1ccc2CN(CCc2c1)C(=O)c1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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