| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50117882 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1514064 (CHEMBL3614202) |
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| Ki | 17±n/a nM |
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| Citation |  Spadoni, G; Bedini, A; Lucarini, S; Mari, M; Caignard, DH; Boutin, JA; Delagrange, P; Lucini, V; Scaglione, F; Lodola, A; Zanardi, F; Pala, D; Mor, M; Rivara, S Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines. J Med Chem58:7512-25 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50117882 |
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| n/a |
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| Name | BDBM50117882 |
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| Synonyms: | CHEMBL3612464 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N2O2 |
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| Mol. Mass. | 338.4433 |
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| SMILES | CCC(=O)NCC1CCc2c(OC)cccc2N1Cc1ccccc1 |
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| Structure | 
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