| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 40 member 1 |
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| Ligand | BDBM50120969 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1520975 (CHEMBL3624279) |
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| EC50 | 599±n/a nM |
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| Citation |  Chua, K; Fung, E; Micewicz, ED; Ganz, T; Nemeth, E; Ruchala, P Small cyclic agonists of iron regulatory hormone hepcidin. Bioorg Med Chem Lett25:4961-9 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 40 member 1 |
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| Name: | Solute carrier family 40 member 1 |
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| Synonyms: | FPN | FPN1 | FPN1 | Ferroportin-1 | IREG1 | Iron-regulated transporter 1 | S40A1_HUMAN | SLC11A3 | SLC40A1 | Solute carrier family 40 member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62541.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109560 |
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| Residue: | 571 |
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| Sequence: | MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLL
TAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHEL
LTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRI
DQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLK
EEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV
SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAF
TWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITP
TKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLL
QENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFR
FAQNTLGNKLFACGPDAKEVRKENQANTSVV
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| BDBM50120969 |
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| n/a |
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| Name | BDBM50120969 |
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| Synonyms: | CHEMBL3623063 |
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| Type | Small organic molecule |
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| Emp. Form. | C54H75N15O9S3 |
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| Mol. Mass. | 1174.463 |
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| SMILES | [H][C@@]12CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CSCc1ccccc1CSC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(N)=O)NC(C)=O |r| |
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| Structure | 
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