| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50300828 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1521958 (CHEMBL3626982) |
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| Ki | 4.8±n/a nM |
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| Citation |  Karila, D; Freret, T; Bouet, V; Boulouard, M; Dallemagne, P; Rochais, C Therapeutic Potential of 5-HT6 Receptor Agonists. J Med Chem58:7901-12 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50300828 |
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| n/a |
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| Name | BDBM50300828 |
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| Synonyms: | 2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)-N,N-dimethylethanamine | CHEMBL571858 | N-(2-{3-[(3-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethyl)-N,N-dimethylamine | WAY-208466 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18FN3O2S |
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| Mol. Mass. | 347.407 |
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| SMILES | CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |
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| Structure | 
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