| Reaction Details |
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 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 2 |
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| Ligand | BDBM50030791 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1523462 (CHEMBL3630806) |
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| IC50 | >250000±n/a nM |
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| Citation |  Dounay, AB; Tuttle, JB; Verhoest, PR Challenges and Opportunities in the Discovery of New Therapeutics Targeting the Kynurenine Pathway. J Med Chem58:8762-82 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Indoleamine 2,3-dioxygenase 2 |
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| Name: | Indoleamine 2,3-dioxygenase 2 |
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| Synonyms: | I23O2_HUMAN | IDO-2 | IDO2 | INDOL1 | Indoleamine 2,3-dioxygenase-like protein 1 | Indoleamine-pyrrole 2,3-dioxygenase-like protein 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47079.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109909 |
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| Residue: | 420 |
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| Sequence: | MLHFHYYDTSNKIMEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIA
NKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVL
PRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGF
ILVTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDP
DIFYAGIRIFLSGWKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSK
ESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYH
ITMVTKYLITAAAKAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG
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| BDBM50030791 |
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| n/a |
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| Name | BDBM50030791 |
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| Synonyms: | CHEMBL3342402 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N4O3S2 |
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| Mol. Mass. | 424.496 |
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| SMILES | Cc1ccc(cc1)-c1csc2nnc(SCC(=O)Nc3ccc4OCOc4c3)n12 |
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| Structure | 
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