| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM50127639 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1522499 (CHEMBL3631635) |
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| Ki | 3.4±n/a nM |
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| Citation |  de la Fuente Revenga, M; Herrera-Arozamena, C; Fernández-Sáez, N; Barco, G; García-Orue, I; Sugden, D; Rivara, S; Rodríguez-Franco, MI New coumarin-based fluorescent melatonin ligands. Design, synthesis and pharmacological characterization. Eur J Med Chem103:370-3 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50127639 |
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| n/a |
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| Name | BDBM50127639 |
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| Synonyms: | CHEMBL3628489 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H15NO4 |
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| Mol. Mass. | 261.2732 |
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| SMILES | COc1ccc2oc(=O)cc(CCNC(C)=O)c2c1 |
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| Structure | 
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