| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metallo-beta-lactamase VIM-2 |
|---|
| Ligand | BDBM50129081 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1523080 (CHEMBL3631657) |
|---|
| Kd | 274000±n/a nM |
|---|
| Citation |  Christopeit, T; Carlsen, TJ; Helland, R; Leiros, HK Discovery of Novel Inhibitor Scaffolds against the Metallo-ß-lactamase VIM-2 by Surface Plasmon Resonance (SPR) Based Fragment Screening. J Med Chem58:8671-82 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metallo-beta-lactamase VIM-2 |
|---|
| Name: | Metallo-beta-lactamase VIM-2 |
|---|
| Synonyms: | Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 28318.00 |
|---|
| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
|---|
| Description: | n/a |
|---|
| Residue: | 266 |
|---|
| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
|
|
|
|---|
| BDBM50129081 |
|---|
| n/a |
|---|
| Name | BDBM50129081 |
|---|
| Synonyms: | CHEBI:33070 | Indole-3-Butyric Acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H13NO2 |
|---|
| Mol. Mass. | 203.2371 |
|---|
| SMILES | OC(=O)CCCc1c[nH]c2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
