| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50325534 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1525033 (CHEMBL3637631) |
|---|
| Ki | 0.390000±n/a nM |
|---|
| Citation |  Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Conformationally restricted¿-opioid receptor agonists: Synthesis and pharmacological evaluation of diastereoisomeric and enantiomeric decahydroquinoxalines. Bioorg Med Chem Lett25:5326-30 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 11165.58 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | P97266 |
|---|
| Residue: | 98 |
|---|
| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
|
|
|
|---|
| BDBM50325534 |
|---|
| n/a |
|---|
| Name | BDBM50325534 |
|---|
| Synonyms: | CHEMBL267495 | nalfurafine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H32N2O5 |
|---|
| Mol. Mass. | 476.5641 |
|---|
| SMILES | CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 |
|---|
| Structure | 
|
|---|
Search and Browse
