| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 5B, mitochondrial |
|---|
| Ligand | BDBM50362850 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1523554 (CHEMBL3631202) |
|---|
| Ki | 800±n/a nM |
|---|
| Citation |  Maresca, A; Akyuz, G; Osman, SM; AlOthman, Z; Supuran, CT Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters. Bioorg Med Chem23:7181-8 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 5B, mitochondrial |
|---|
| Name: | Carbonic anhydrase 5B, mitochondrial |
|---|
| Synonyms: | CA-VB | CA5B | CAH5B_HUMAN | Carbonate dehydratase VB | Carbonic Anhydrase VB | Carbonic anhydrase 5B (CA VB) | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 5B, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VB (CA VB) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36440.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human (cloned) isozyme |
|---|
| Residue: | 317 |
|---|
| Sequence: | MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPG
GDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL
EHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVI
GVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLS
ESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDY
VLNVQAKPKPATSQATP
|
|
|
|---|
| BDBM50362850 |
|---|
| n/a |
|---|
| Name | BDBM50362850 |
|---|
| Synonyms: | CHEMBL1095574 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14O3 |
|---|
| Mol. Mass. | 254.2806 |
|---|
| SMILES | Oc1ccc(\C=C\C(=O)OCc2ccccc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
