| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Proteinase-activated receptor 1 |
|---|
| Ligand | BDBM50079756 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1539211 (CHEMBL3739018) |
|---|
| IC50 | 300±n/a nM |
|---|
| Citation |  Chao, B; Li, BX; Xiao, X The chemistry and pharmacology of privileged pyrroloquinazolines. Medchemcomm6:510-520 (2015) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Proteinase-activated receptor 1 |
|---|
| Name: | Proteinase-activated receptor 1 |
|---|
| Synonyms: | CF2R | Coagulation factor II receptor | F2R | PAR-1 | PAR1 | PAR1_HUMAN | Proteinase activated receptor 1 | Proteinase-activated receptor 1 (PAR-1) | TR | Thrombin receptor | Thrombin receptor/ Proteinase-activated receptor 1(Par-1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 47450.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P25116 |
|---|
| Residue: | 425 |
|---|
| Sequence: | MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEE
KNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLN
IMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTA
AFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLK
EQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSS
AVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVS
SISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIY
KKLLT
|
|
|
|---|
| BDBM50079756 |
|---|
| n/a |
|---|
| Name | BDBM50079756 |
|---|
| Synonyms: | 7-(4-Isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine | CHEMBL292089 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H21N5 |
|---|
| Mol. Mass. | 331.4142 |
|---|
| SMILES | CC(C)c1ccc(Cn2ccc3c2ccc2nc(N)nc(N)c32)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
