| Reaction Details |
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 | Report a problem with these data |
| Target | CviR transcriptional regulator |
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| Ligand | BDBM50136219 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1547614 (CHEMBL3755484) |
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| IC50 | 90900±n/a nM |
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| Citation |  Bucio-Cano, A; Reyes-Arellano, A; Correa-Basurto, J; Bello, M; Torres-Jaramillo, J; Salgado-Zamora, H; Curiel-Quesada, E; Peralta-Cruz, J; Avila-Sorrosa, A Targeting quorum sensing by designing azoline derivatives to inhibit the N-hexanoyl homoserine lactone-receptor CviR: Synthesis as well as biological and theoretical evaluations. Bioorg Med Chem23:7565-77 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| CviR transcriptional regulator |
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| Name: | CviR transcriptional regulator |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29723.76 |
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| Organism: | Chromobacterium violaceum |
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| Description: | ChEMBL_765227 |
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| Residue: | 265 |
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| Sequence: | MVISKPINARPLPAGLTASQQWTLLEWIHMAGHIETENELKAFLDQVLSQAPSERLLLAL
GRLNNQNQIQRLERVLNVSYPSDWLDQYMKENYAQHDPILRIHLGQGPVMWEERFNRAKG
AEEKRFIAEATQNGMGSGITFSAASERNNIGSILSIAGREPGRNAALVAMLNCLTPHLHQ
AAIRVANLPPASPSNMPLSQREYDIFHWMSRGKTNWEIATILDISERTVKFHVANVIRKL
NANNRTHAIVLGMHLAMPPSTVANE
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| BDBM50136219 |
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| n/a |
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| Name | BDBM50136219 |
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| Synonyms: | CHEMBL3753564 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22N2O |
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| Mol. Mass. | 246.348 |
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| SMILES | CCCCCCOc1ccc(cc1)C1=NCCN1 |t:14| |
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| Structure | 
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