| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50137519 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1549261 (CHEMBL3757839) |
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| IC50 | >30000±n/a nM |
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| Citation |  Federico, S; Ciancetta, A; Porta, N; Redenti, S; Pastorin, G; Cacciari, B; Klotz, KN; Moro, S; Spalluto, G 5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors. Eur J Med Chem108:529-41 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50137519 |
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| n/a |
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| Name | BDBM50137519 |
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| Synonyms: | CHEMBL3754760 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17N7O2 |
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| Mol. Mass. | 363.3733 |
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| SMILES | CC(C)Nc1nc(NC(=O)c2ccccc2)n2nc(nc2n1)-c1ccco1 |
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| Structure | 
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