| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50138718 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1550086 (CHEMBL3756032) |
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| Ki | >10000±n/a nM |
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| Citation |  Squarcialupi, L; Catarzi, D; Varano, F; Betti, M; Falsini, M; Vincenzi, F; Ravani, A; Ciancetta, A; Varani, K; Moro, S; Colotta, V Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor. Eur J Med Chem108:117-33 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36643.73 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_479910 |
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| Residue: | 320 |
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| Sequence: | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALAD
IAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRY
RTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMV
FFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFL
FALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILR
ACRLCQTSDSLDSNLEQTTE
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| BDBM50138718 |
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| n/a |
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| Name | BDBM50138718 |
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| Synonyms: | CHEMBL3751909 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H19N5O2 |
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| Mol. Mass. | 421.4507 |
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| SMILES | COc1ccc(cc1)-c1nc(NC(=O)c2ccccc2)c2nn(cc2n1)-c1ccccc1 |
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| Structure | 
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