| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM1894 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1553166 |
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| IC50 | 900±n/a nM |
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| Citation |  Das, D; Sikdar, P; Bairagi, M Recent developments of 2-aminothiazoles in medicinal chemistry. Eur J Med Chem109:89-98 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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|
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| BDBM1894 |
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| n/a |
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| Name | BDBM1894 |
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| Synonyms: | 1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiourea | CHEMBL33981 | LY73497 | N-(2-phenethyl)-N -(2-thiazolyl)thiourea | Phenylethylthiazolylthiourea (PETT) Analog |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13N3S2 |
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| Mol. Mass. | 263.382 |
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| SMILES | S=C(NCCc1ccccc1)Nc1nccs1 |
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| Structure | 
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