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TargetVitamin D3 receptor
LigandBDBM50375596
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1553653 (CHEMBL3766233)
EC50>150000±n/a nM
Citation Teske, KABogart, JWSanchez, LMYu, OBPreston, JVCook, JMSilvaggi, NRBikle, DDArnold, LA Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites. Eur J Med Chem109:238-46 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Vitamin D3 receptor
Name:Vitamin D3 receptor
Synonyms:1,25-dihydroxyvitamin D3 receptor | NR1I1 | Nuclear receptor subfamily 1 group I member 1 | Retinoic acid receptor RXR-alpha/Vitamin D3 receptor | VDR | VDR_HUMAN
Type:Protein
Mol. Mass.:48288.72
Organism:Homo sapiens (Human)
Description:P11473
Residue:427
Sequence:
MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
VFGNEIS
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  Blast E-value cutoff:
BDBM50375596
n/a
NameBDBM50375596
Synonyms:HDCA | hyodeoxycholic acid
TypeSmall organic molecule
Emp. Form.C24H40O4
Mol. Mass.392.572
SMILESC[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Structure
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