Reaction Details |
| Report a problem with these data |
Target | Melatonin receptor type 1B |
---|
Ligand | BDBM50139841 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_1553993 |
---|
Ki | 1.2±n/a nM |
---|
Citation | Couhert, A; Delagrange, P; Caignard, DH; Chartier, A; Suzenet, F; Guillaumet, G Synthesis of 2-arylfuro[3,2-b]pyridines: Effect of the C2-aryl group on melatoninergic activity. Eur J Med Chem109:268-75 (2016) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Melatonin receptor type 1B |
---|
Name: | Melatonin receptor type 1B |
Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
Type: | Enzyme |
Mol. Mass.: | 40203.54 |
Organism: | Homo sapiens (Human) |
Description: | P49286 |
Residue: | 362 |
Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
|
|
|
BDBM50139841 |
---|
n/a |
---|
Name | BDBM50139841 |
Synonyms: | CHEMBL3763281 |
Type | Small organic molecule |
Emp. Form. | C12H14N2O3 |
Mol. Mass. | 234.2512 |
SMILES | COc1ccc2occ(CCNC(C)=O)c2n1 |
Structure |
|