| Reaction Details |
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 | Report a problem with these data |
| Target | S-adenosylhomocysteine hydrolase-like protein 1 |
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| Ligand | BDBM50140074 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1547422 (CHEMBL3757541) |
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| IC50 | 2.7±n/a nM |
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| Citation |  Liu, C; Chen, Q; Schneller, SW Enantiomeric 3-deaza-1',6'-isoneplanocin and its 3-bromo analogue: Synthesis by the Ullmann reaction and their antiviral properties. Bioorg Med Chem Lett26:928-30 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| S-adenosylhomocysteine hydrolase-like protein 1 |
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| Name: | S-adenosylhomocysteine hydrolase-like protein 1 |
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| Synonyms: | AHCYL1 | Adenosylhomocysteinase 2 | AdoHcyase 2 | DC-expressed AHCY-like molecule | DCAL | DCAL | IP(3)Rs binding protein released with IP(3) | IRBIT | SAHH2_HUMAN | XPVKONA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58952.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116703 |
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| Residue: | 530 |
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| Sequence: | MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
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| BDBM50140074 |
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| n/a |
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| Name | BDBM50140074 |
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| Synonyms: | CHEMBL2059155 | US10227373, Compound 3-Bromo-3-deazaneplanocin |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13BrN4O3 |
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| Mol. Mass. | 341.161 |
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| SMILES | Nc1ncc(Br)c2n(cnc12)[C@@H]1C=C(CO)[C@@H](O)[C@H]1O |r,t:14| |
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| Structure | 
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