| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 1 |
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| Ligand | BDBM50140247 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1548130 (CHEMBL3754932) |
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| Ki | 2.0±n/a nM |
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| Citation |  Wójcik, P; Berlicki, L Peptide-based inhibitors of protein-protein interactions. Bioorg Med Chem Lett26:707-13 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bcl-2-like protein 1 |
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| Name: | Bcl-2-like protein 1 |
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| Synonyms: | Anti-apoptotic Bcl-2 protein | Apoptosis Regulator Bcl-xL | Apoptosis regulator Bcl-X | B2CL1_HUMAN | BCL2-like 1 isoform 1 | BCL2L | BCL2L1 | BCLX | Bcl-2-like protein 1 (Bcl-XL) | Bcl-X | Bcl-xL/Bcl-2-binding component 3 | Bcl2-L-1 | Bcl2-antagonist of cell death (BAD) |
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| Type: | Mitochondrion membrane; Single-pass membrane protein |
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| Mol. Mass.: | 26039.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 233 |
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| Sequence: | MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA
DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY
QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP
WIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
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| BDBM50140247 |
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| n/a |
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| Name | BDBM50140247 |
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| Synonyms: | CHEMBL3754255 |
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| Type | Small organic molecule |
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| Emp. Form. | C80H131N25O19 |
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| Mol. Mass. | 1747.0522 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H]1CCC[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1CCC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCC[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]1CNC[C@@H]1NC(C)=O)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| |
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| Structure | 
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