| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50146584 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1555061 (CHEMBL3767807) |
|---|
| Ki | 3.6±n/a nM |
|---|
| Citation |  Abate, C; Riganti, C; Pati, ML; Ghigo, D; Berardi, F; Mavlyutov, T; Guo, LW; Ruoho, A Development of sigma-1 (s1) receptor fluorescent ligands as versatile tools to studys1 receptors. Eur J Med Chem108:577-85 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 25307.17 |
|---|
| Organism: | Cavia porcellus (Guinea pig) |
|---|
| Description: | Q60492 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
|
|
|
|---|
| BDBM50146584 |
|---|
| n/a |
|---|
| Name | BDBM50146584 |
|---|
| Synonyms: | CHEMBL3765740 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H51N3O3 |
|---|
| Mol. Mass. | 573.8084 |
|---|
| SMILES | CC1CCN(CCCCC2CCCc3cc(OCCCCCCN4C(=O)c5ccc(cc5C4=O)N(C)C)ccc23)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
