| Reaction Details |
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 | Report a problem with these data |
| Target | Calcitonin gene-related peptide 1 |
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| Ligand | BDBM50150345 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1558562 (CHEMBL3773899) |
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| IC50 | 130±n/a nM |
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| Citation |  Civiello, RL; Han, X; Beno, BR; Chaturvedula, PV; Herbst, JJ; Xu, C; Conway, CM; Macor, JE; Dubowchik, GM Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines. Bioorg Med Chem Lett26:1229-32 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcitonin gene-related peptide 1 |
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| Name: | Calcitonin gene-related peptide 1 |
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| Synonyms: | CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 13902.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06881 |
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| Residue: | 128 |
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| Sequence: | MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
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| BDBM50150345 |
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| n/a |
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| Name | BDBM50150345 |
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| Synonyms: | CHEMBL3770044 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H42FN7O2 |
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| Mol. Mass. | 575.72 |
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| SMILES | Cc1cc(C[C@@H](NC(=O)N2CCN(CC2)c2ccccc2F)C(=O)N2CCC(CC2)N2CCCCC2)cc2cn[nH]c12 |r| |
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| Structure | 
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