Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50151272 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1559078 (CHEMBL3773934) |
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Ki | 0.741310±n/a nM |
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Citation | Franchini, S; Battisti, UM; Prandi, A; Tait, A; Borsari, C; Cichero, E; Fossa, P; Cilia, A; Prezzavento, O; Ronsisvalle, S; Aricò, G; Parenti, C; Brasili, L Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives. Eur J Med Chem112:1-19 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
Type: | Protein |
Mol. Mass.: | 25307.17 |
Organism: | Cavia porcellus (Guinea pig) |
Description: | Q60492 |
Residue: | 223 |
Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50151272 |
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n/a |
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Name | BDBM50151272 |
Synonyms: | CHEMBL3769930 |
Type | Small organic molecule |
Emp. Form. | C20H30N2O2 |
Mol. Mass. | 330.4644 |
SMILES | C(C1COC2(CCCCC2)O1)N1CCN(Cc2ccccc2)CC1 |
Structure |
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