| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase type 2 |
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| Ligand | BDBM21642 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1567671 (CHEMBL3792099) |
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| Kd | 14125±n/a nM |
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| Citation |  Christopeit, T; Leiros, HK Fragment-based discovery of inhibitor scaffolds targeting the metallo-ß-lactamases NDM-1 and VIM-2. Bioorg Med Chem Lett26:1973-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Metallo-beta-lactamase type 2 |
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| Name: | Metallo-beta-lactamase type 2 |
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| Synonyms: | B2 metallo-beta-lactamase | BLAN1_KLEPN | Beta-lactamase NDM-1 | Beta-lactamase type II | Metallo-beta-lactamase NDM-1 | Metallo-beta-lactamase type 2 | Metallo-beta-lactamase type II | NDM-1 | New Delhi metallo-beta-lactamase-1 | blaNDM-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28498.15 |
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| Organism: | Klebsiella pneumoniae |
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| Description: | ChEMBL_103887 |
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| Residue: | 270 |
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| Sequence: | MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQ
HTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTH
AHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPL
KVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAF
PKASMIVMSHSAPDSRAAITHTARMADKLR
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| BDBM21642 |
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| n/a |
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| Name | BDBM21642 |
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| Synonyms: | (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid | CHEMBL1560 | Capozide | Captopril | Lopirin | SQ 14,225 | SQ14534 | US11491146, Compound L-Captopril |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15NO3S |
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| Mol. Mass. | 217.285 |
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| SMILES | C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O |
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| Structure | 
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