| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50161822 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1567954 (CHEMBL3789811) |
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| IC50 | >200000±n/a nM |
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| Citation |  Viira, B; Selyutina, A; García-Sosa, AT; Karonen, M; Sinkkonen, J; Merits, A; Maran, U Design, discovery, modelling, synthesis, and biological evaluation of novel and small, low toxicity s-triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorg Med Chem24:2519-29 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
|
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|
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| BDBM50161822 |
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| n/a |
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| Name | BDBM50161822 |
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| Synonyms: | CHEMBL3787152 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N6 |
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| Mol. Mass. | 320.3916 |
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| SMILES | CNc1nc(Nc2ccc(C)cc2)nc(Nc2ccc(C)cc2)n1 |
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| Structure | 
|
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