| Reaction Details |
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 | Report a problem with these data |
| Target | Prostacyclin receptor |
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| Ligand | BDBM50163306 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1570587 (CHEMBL3794955) |
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| IC50 | 430±n/a nM |
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| Citation |  Hayashi, R; Sakagami, H; Koiwa, M; Ito, H; Miyamoto, M; Isogaya, M Piperidine derivatives as nonprostanoid IP receptor agonists. Bioorg Med Chem Lett26:2360-4 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostacyclin receptor |
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| Name: | Prostacyclin receptor |
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| Synonyms: | PGI receptor | PI2R_HUMAN | PRIPR | PTGIR | Prostacyclin (IP) Receptor | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Prostaglandin I2 receptor | Prostanoid IP receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40968.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The membranes prepared from human platelet were used in binding assay. |
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| Residue: | 386 |
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| Sequence: | MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
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| BDBM50163306 |
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| n/a |
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| Name | BDBM50163306 |
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| Synonyms: | CHEMBL3793117 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N2O4 |
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| Mol. Mass. | 410.506 |
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| SMILES | CCc1ccc(cc1)N(CCN1CCC(CC1)OCC(O)=O)C(=O)c1ccccc1 |
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| Structure | 
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