| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
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| Ligand | BDBM50166588 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1576574 (CHEMBL3804489) |
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| IC50 | >1000±n/a nM |
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| Citation |  Katoh, T; Takai, T; Yukawa, T; Tsukamoto, T; Watanabe, E; Mototani, H; Arita, T; Hayashi, H; Nakagawa, H; Klein, MG; Zou, H; Sang, BC; Snell, G; Nakada, Y Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKC¿ inhibitors. Bioorg Med Chem24:2466-75 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform delta |
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| Name: | Casein kinase I isoform delta |
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| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47356.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48730 |
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| Residue: | 415 |
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| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
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| BDBM50166588 |
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| n/a |
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| Name | BDBM50166588 |
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| Synonyms: | CHEMBL3798011 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23N5O2 |
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| Mol. Mass. | 413.4717 |
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| SMILES | C[C@@H](N1c2cc(ccc2C(=O)NC1(C)C)-n1c2cccnc2[nH]c1=O)c1ccccc1 |r| |
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| Structure | 
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