| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50166978 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1573520 (CHEMBL3801475) |
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| Ki | 860±n/a nM |
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| Citation |  Weichert, D; Stanek, M; Hübner, H; Gmeiner, P Structure-guided development of dualß2 adrenergic/dopamine D2 receptor agonists. Bioorg Med Chem24:2641-53 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50166978 |
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| n/a |
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| Name | BDBM50166978 |
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| Synonyms: | CHEMBL3800636 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31NO4 |
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| Mol. Mass. | 421.5286 |
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| SMILES | COc1cc(CCNCCc2ccc(O)c(O)c2)ccc1OCCCc1ccccc1 |
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| Structure | 
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