| Reaction Details |
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 | Report a problem with these data |
| Target | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
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| Ligand | BDBM50168921 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1577532 (CHEMBL3806941) |
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| Ki | 7200±n/a nM |
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| Citation |  Ai, T; Wilson, DJ; More, SS; Xie, J; Chen, L 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. J Med Chem59:2928-41 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
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| Name: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
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| Synonyms: | NAD-dependent deacetylase sirtuin 3 | NAD-dependent protein deacetylase sirtuin-3 (SIRT3) | SIR2L3 | SIR3_HUMAN | SIRT3 |
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| Type: | Protein |
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| Mol. Mass.: | 43582.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NTG7 |
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| Residue: | 399 |
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| Sequence: | MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEP
LDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK
GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIF
ELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIP
ASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ
RFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDV
AQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK
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| BDBM50168921 |
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| n/a |
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| Name | BDBM50168921 |
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| Synonyms: | CHEMBL3806257 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16N4O3 |
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| Mol. Mass. | 348.3553 |
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| SMILES | NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccncc3)c2)c1 |
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| Structure | 
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