| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-7 |
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| Ligand | BDBM50171564 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1577038 (CHEMBL3807014) |
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| IC50 | >200000±n/a nM |
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| Citation |  Deng, CB; Li, J; Li, LY; Sun, FJ Protective effect of novel substituted nicotine hydrazide analogues against hypoxic brain injury in neonatal rats via inhibition of caspase. Bioorg Med Chem Lett26:3195-201 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-7 |
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| Name: | Caspase-7 |
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| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
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| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
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| BDBM50171564 |
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| n/a |
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| Name | BDBM50171564 |
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| Synonyms: | CHEMBL3805555 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N4O4 |
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| Mol. Mass. | 430.4559 |
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| SMILES | COc1ccc(cc1OC)-c1ccc(C(=O)N\N=C2/C(=O)N(C)c3ccccc23)c(C)n1 |
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| Structure | 
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