| Reaction Details |
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 | Report a problem with these data |
| Target | Histone-lysine N-methyltransferase SETD7 |
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| Ligand | BDBM50173506 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1580421 (CHEMBL3812774) |
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| IC50 | 7200±n/a nM |
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| Citation |  Takemoto, Y; Ito, A; Niwa, H; Okamura, M; Fujiwara, T; Hirano, T; Handa, N; Umehara, T; Sonoda, T; Ogawa, K; Tariq, M; Nishino, N; Dan, S; Kagechika, H; Yamori, T; Yokoyama, S; Yoshida, M Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription. J Med Chem59:3650-60 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone-lysine N-methyltransferase SETD7 |
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| Name: | Histone-lysine N-methyltransferase SETD7 |
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| Synonyms: | Histone-lysine N-methyltransferase SETD7 | KIAA1717 | KMT7 | SET domain-containing protein 7/9 (Set7/9) | SET7 | SET9 | SETD7 | SETD7_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 40691.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WTS6 |
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| Residue: | 366 |
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| Sequence: | MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE
GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW
IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP
HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT
VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT
PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF
QATQQK
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| BDBM50173506 |
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| n/a |
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| Name | BDBM50173506 |
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| Synonyms: | CHEMBL3809236 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N |
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| Mol. Mass. | 301.4247 |
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| SMILES | [#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]=[#6]-c2ccccc-12 |c:17| |
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| Structure | 
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