| Reaction Details |
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 | Report a problem with these data |
| Target | Follicle-stimulating hormone receptor |
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| Ligand | BDBM50173580 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1580950 (CHEMBL3812618) |
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| EC50 | <100±n/a nM |
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| Citation |  Abdel-Magid, AF Targeting the Follicle Stimulating Hormone Receptor (FSHR) To Treat Fertility Disorders. ACS Med Chem Lett7:345-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Follicle-stimulating hormone receptor |
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| Name: | Follicle-stimulating hormone receptor |
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| Synonyms: | FSH-R | FSHR | FSHR_HUMAN | Follicle stimulating hormone receptor | Follicle-stimulating hormone receptor | Follitropin receptor | LGR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78273.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1351769 |
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| Residue: | 695 |
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| Sequence: | MALLLVSLLAFLSLGSGCHHRICHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRV
IQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLP
NLQYLLISNTGIKHLPDVHKIHSLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKN
GIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGASGPVILDISRTRIHSLPSYGLEN
LKKLRARSTYNLKKLPTLEKLVALMEASLTYPSHCCAFANWRRQISELHPICNKSILRQE
VDYMTQARGQRSSLAEDNESSYSRGFDMTYTEFDYDLCNEVVDVTCSPKPDAFNPCEDIM
GYNILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIAS
VDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCK
VQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVL
AFVVICGCYIHIYLTVRNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLKVP
LITVSKAKILLVLFHPINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIYRTETSS
TVHNTHPRNGHCSSAPRVTNGSTYILVPLSHLAQN
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| BDBM50173580 |
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| n/a |
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| Name | BDBM50173580 |
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| Synonyms: | CHEMBL3808949 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H36N6O4 |
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| Mol. Mass. | 544.6446 |
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| SMILES | Cc1ccccc1N1CCN(CC1)c1ccc(cc1NC(=O)c1ccco1)C(=O)NCCCNC(=O)NCC=C |
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| Structure | 
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