Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50174032 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1581396 (CHEMBL3812003) |
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Ki | 4.7±n/a nM |
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Citation | Shen, Q; Qian, Y; Huang, X; Xu, X; Li, W; Liu, J; Fu, W Discovery of Potent and Selective Agonists ofd Opioid Receptor by Revisiting the"Message-Address" Concept. ACS Med Chem Lett7:391-6 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50174032 |
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n/a |
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Name | BDBM50174032 |
Synonyms: | CHEMBL3808835 |
Type | Small organic molecule |
Emp. Form. | C26H29NO3 |
Mol. Mass. | 403.5134 |
SMILES | COc1ccccc1-c1ccc2c(CC[C@H](CN(C)C)[C@@]2(O)c2cccc(O)c2)c1 |r| |
Structure |
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