| Reaction Details |
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 | Report a problem with these data |
| Target | Segment polarity protein dishevelled homolog DVL-1 |
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| Ligand | BDBM50177708 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1583392 (CHEMBL3816124) |
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| Kd | 2.0±n/a nM |
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| Citation |  Choi, J; Ma, S; Kim, HY; Yun, JH; Heo, JN; Lee, W; Choi, KY; No, KT Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies. Bioorg Med Chem24:3259-66 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Segment polarity protein dishevelled homolog DVL-1 |
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| Name: | Segment polarity protein dishevelled homolog DVL-1 |
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| Synonyms: | DSH homolog 1 | DVL1 | DVL1_HUMAN | Dishevelled-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 75195.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_468588 |
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| Residue: | 695 |
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| Sequence: | MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK
EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF
HPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSAST
ALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSI
TDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDM
LLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDP
AAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAVVR
VMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFL
RHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPY
QYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGS
GSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGG
PPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
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| BDBM50177708 |
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| n/a |
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| Name | BDBM50177708 |
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| Synonyms: | CHEMBL3814619 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19NO5S2 |
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| Mol. Mass. | 429.509 |
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| SMILES | CCOc1cc(\C=C2/SC(=S)N(Cc3ccccc3)C2=O)ccc1OCC(O)=O |
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| Structure | 
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