| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50092612 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1586603 (CHEMBL3821824) |
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| Ki | 75±n/a nM |
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| Citation |  Mujumdar, P; Teruya, K; Tonissen, KF; Vullo, D; Supuran, CT; Peat, TS; Poulsen, SA An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C. J Med Chem59:5462-70 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 35037.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22748 |
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| Residue: | 312 |
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| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
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| BDBM50092612 |
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| n/a |
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| Name | BDBM50092612 |
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| Synonyms: | CHEMBL3586274 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14BrN3O5S |
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| Mol. Mass. | 380.215 |
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| SMILES | NS(=O)(=O)CCNC(=O)C(\Cc1ccc(O)c(Br)c1)=N\O |
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| Structure | 
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