| Reaction Details |
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 | Report a problem with these data |
| Target | Ectonucleoside triphosphate diphosphohydrolase 2 |
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| Ligand | BDBM50187685 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1590660 (CHEMBL3829421) |
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| IC50 | 3000±n/a nM |
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| Citation |  Fiene, A; Baqi, Y; Malik, EM; Newton, P; Li, W; Lee, SY; Hartland, EL; Müller, CE Inhibitors for the bacterial ectonucleotidase Lp1NTPDase from Legionella pneumophila. Bioorg Med Chem24:4363-4371 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ectonucleoside triphosphate diphosphohydrolase 2 |
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| Name: | Ectonucleoside triphosphate diphosphohydrolase 2 |
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| Synonyms: | CD39L1 | ENTP2_HUMAN | ENTPD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53675.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1453714 |
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| Residue: | 495 |
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| Sequence: | MAGKVRSLLPPLLLAAAGLAGLLLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPA
DKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLG
ATAGMRLLNLTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENF
IKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSF
LCYGRDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVS
LSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMG
LPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAF
GGVIFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALV
LLLRQVHSAKLPSTI
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| BDBM50187685 |
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| n/a |
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| Name | BDBM50187685 |
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| Synonyms: | CHEMBL597418 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H17N2NaO5S |
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| Mol. Mass. | 516.5 |
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| SMILES | [Na+].Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2cc3ccccc3c3ccccc23)cc1S([O-])(=O)=O |
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| Structure | 
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