| Reaction Details |
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 | Report a problem with these data |
| Target | Proto-oncogene tyrosine-protein kinase Src |
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| Ligand | BDBM50196884 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1618939 (CHEMBL3861108) |
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| IC50 | 28200±n/a nM |
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| Citation |  Wang, YD; Bao, XQ; Xu, S; Yu, WW; Cao, SN; Hu, JP; Li, Y; Wang, XL; Zhang, D; Yu, SS A Novel Parkinson's Disease Drug Candidate with Potent Anti-neuroinflammatory Effects through the Src Signaling Pathway. J Med Chem59:9062-9079 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proto-oncogene tyrosine-protein kinase Src |
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| Name: | Proto-oncogene tyrosine-protein kinase Src |
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| Synonyms: | Neuronal proto-oncogene tyrosine-protein kinase Src | Proto-oncogene c-Src | SRC_MOUSE | Src | Tyrosine-protein kinase SRC | pp60c-src (p60-Src) |
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| Type: | Protein |
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| Mol. Mass.: | 59894.66 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P05480 |
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| Residue: | 535 |
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| Sequence: | MGSNKSKPKDASQRRRSLEPSENVHGAGGAFPASQTPSKPASADGHRGPSAAFVPPAAEP
KLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDW
WLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESE
TTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLC
HRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLK
PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYL
RLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA
RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERG
YRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
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| BDBM50196884 |
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| n/a |
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| Name | BDBM50196884 |
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| Synonyms: | CHEMBL3985713 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H32ClNO4 |
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| Mol. Mass. | 373.915 |
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| SMILES | Cl.COc1ccc(C(=O)CC(C)C)c(OC[C@H](O)CNC(C)(C)C)c1 |r| |
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| Structure | 
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