| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
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| Ligand | BDBM50198027 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1620450 (CHEMBL3862733) |
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| Kd | 480±n/a nM |
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| Citation |  Kilchmann, F; Marcaida, MJ; Kotak, S; Schick, T; Boss, SD; Awale, M; Gönczy, P; Reymond, JL Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening. J Med Chem59:7188-211 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
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| Name: | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
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| Synonyms: | PI(5)P 4-kinase type II gamma | PI42C_HUMAN | PIP4K2C | PIP4KII-gamma | PIP5K2C | Phosphatidylinositol-5-phosphate 4-kinase type II gamma | Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47302.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774614 |
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| Residue: | 421 |
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| Sequence: | MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
A
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| BDBM50198027 |
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| n/a |
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| Name | BDBM50198027 |
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| Synonyms: | CHEMBL3921246 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H21N5O3S |
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| Mol. Mass. | 459.52 |
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| SMILES | CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(Nc3ccc(cn3)C(O)=O)c2)C(=O)N1C |
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| Structure | 
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