Reaction Details |
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Target | CDGSH iron-sulfur domain-containing protein 1 |
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Ligand | BDBM25902 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1620947 (CHEMBL3863230) |
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IC50 | 53460±n/a nM |
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Citation | Geldenhuys, WJ; Yonutas, HM; Morris, DL; Sullivan, PG; Darvesh, AS; Leeper, TC Identification of small molecules that bind to the mitochondrial protein mitoNEET. Bioorg Med Chem Lett26:5350-5353 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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CDGSH iron-sulfur domain-containing protein 1 |
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Name: | CDGSH iron-sulfur domain-containing protein 1 |
Synonyms: | C10orf70 | CISD1 | CISD1_HUMAN | MitoNEET | ZCD1 |
Type: | PROTEIN |
Mol. Mass.: | 12206.48 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_766432 |
Residue: | 108 |
Sequence: | MSLTSSSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKAMINLHIQKDNPKIVHAF
DMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
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BDBM25902 |
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n/a |
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Name | BDBM25902 |
Synonyms: | 4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid | CHEMBL35 | Frusemide | Furanthril | Furosemide | Furosemide (3) | Furosemide, 4 | Lasix | US10172837, Furosemide |
Type | Small organic molecule |
Emp. Form. | C12H11ClN2O5S |
Mol. Mass. | 330.744 |
SMILES | NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl |
Structure |
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