| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 2 |
|---|
| Ligand | BDBM50200526 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1622442 (CHEMBL3864794) |
|---|
| Ki | 50±n/a nM |
|---|
| Citation |  Szymanska, E; Chalupnik, P; Szczepanska, K; Cuņado Moral, AM; Pickering, DS; Nielsen, B; Johansen, TN; Kiec-Kononowicz, K Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands. Bioorg Med Chem Lett26:5568-5572 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glutamate receptor ionotropic, kainate 2 |
|---|
| Name: | Glutamate receptor ionotropic, kainate 2 |
|---|
| Synonyms: | EAA4 | Excitatory amino acid receptor 4 | GLUR6 | GRIK2 | GRIK2_HUMAN | GluK2 | GluR-6 | Glutamate kainate | Glutamate receptor 6 | Glutamate receptor ionotropic kainate 2 | Glutamate receptor, ionotropic kainate 2 | Glutamate-Kainate | Glutamate-Kainate, GluR6 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 102592.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13002 |
|---|
| Residue: | 908 |
|---|
| Sequence: | MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFA
VNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQS
ICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDST
GLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILK
QALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMER
LQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFM
SLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGK
PANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEI
RLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISI
LYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSD
VVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLT
VERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKS
NEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITI
AILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVG
EFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRR
LPGKETMA
|
|
|
|---|
| BDBM50200526 |
|---|
| n/a |
|---|
| Name | BDBM50200526 |
|---|
| Synonyms: | CHEMBL1234118 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H24F2N2O4 |
|---|
| Mol. Mass. | 346.3696 |
|---|
| SMILES | OC(=O)[C@@H]1CC(F)(F)CN1C[C@H]1CC[C@H]2CN[C@@H](C[C@H]2C1)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
