| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 5 |
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| Ligand | BDBM50200526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1622443 (CHEMBL3864795) |
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| Ki | 8900±n/a nM |
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| Citation |  Szymanska, E; Chalupnik, P; Szczepanska, K; Cuņado Moral, AM; Pickering, DS; Nielsen, B; Johansen, TN; Kiec-Kononowicz, K Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands. Bioorg Med Chem Lett26:5568-5572 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor ionotropic, kainate 5 |
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| Name: | Glutamate receptor ionotropic, kainate 5 |
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| Synonyms: | GRIK2 | GRIK5 | GRIK5_HUMAN | Glutamate receptor ionotropic kainate 5 | Glutamate receptor, ionotropic kainate 5 | Glutamate-Kainate 5 | Ionotropic glutamate receptor kainate 2/5 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 109280.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Glutamate-Kainate 5 Grik5 HUMAN::Q16478 |
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| Residue: | 980 |
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| Sequence: | MPAELLLLLIVAFASPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAK
ARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKV
GPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRG
FLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLILRKASELGMTSAFY
KYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYLGP
ALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTG
RVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVT
TILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGS
WTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLD
PFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPV
GGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLAD
QTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFL
LESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKR
KWWEGGRCPKEEDHRAKGLGMENIGGIFIVLICGLIIAVFVAVMEFIWSTRRSAESEEVS
VCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLYSAGAGGDAG
SAHGGPQRLLDDPGPPSGARPAAPTPCTHVRVCQECRRIQALRASGAGAPPRGLGVPAEA
TSPPRPRPGPAGPRELAEHE
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| BDBM50200526 |
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| n/a |
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| Name | BDBM50200526 |
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| Synonyms: | CHEMBL1234118 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24F2N2O4 |
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| Mol. Mass. | 346.3696 |
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| SMILES | OC(=O)[C@@H]1CC(F)(F)CN1C[C@H]1CC[C@H]2CN[C@@H](C[C@H]2C1)C(O)=O |r| |
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| Structure | 
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