| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic alpha-amylase |
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| Ligand | BDBM50202632 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1624744 (CHEMBL3867156) |
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| IC50 | 69400±n/a nM |
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| Citation |  Milella, L; Milazzo, S; De Leo, M; Vera Saltos, MB; Faraone, I; Tuccinardi, T; Lapillo, M; De Tommasi, N; Braca, A a-Glucosidase anda-Amylase Inhibitors from Arcytophyllum thymifolium. J Nat Prod79:2104-12 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic alpha-amylase |
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| Name: | Pancreatic alpha-amylase |
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| Synonyms: | 1,4-alpha-D-glucan glucanohydrolase | AMY2 | AMYP_PIG | Pancreatic α-amylase | Pancreatic α-amylase |
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| Type: | Protein |
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| Mol. Mass.: | 57088.07 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00690 |
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| Residue: | 511 |
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| Sequence: | MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPP
NENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGS
GAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGL
LDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAG
SRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWG
FMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWA
RNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQP
FANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGI
KVYVSSDGTAQFSISNSAEDPFIAIHAESKL
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| BDBM50202632 |
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| n/a |
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| Name | BDBM50202632 |
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| Synonyms: | CHEMBL460030 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24O12 |
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| Mol. Mass. | 432.376 |
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| SMILES | [H][C@]12[C@@H](O)C=C(COC(C)=O)[C@@]1([H])[C@]([H])(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)OC=C2C(O)=O |r,c:30,t:4| |
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| Structure | 
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