| Reaction Details |
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 | Report a problem with these data |
| Target | Thrombin |
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| Ligand | BDBM50432209 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1629275 (CHEMBL3871901) |
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| IC50 | 554±n/a nM |
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| Citation |  Chen, D; Shi, J; Liu, J; Zhang, X; Deng, X; Yang, Y; Cui, S; Zhu, Q; Gong, G; Xu, Y Design, synthesis and antithrombotic evaluation of novel non-peptide thrombin inhibitors. Bioorg Med Chem25:458-470 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thrombin |
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| Name: | Thrombin |
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| Synonyms: | Thrombin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27104.73 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_104556 |
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| Residue: | 235 |
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| Sequence: | QELLCAASLISDRWVLTAAHCLLYPPWDKNFTVNDILVRIGKYARSRYERNMEKISTLEK
IIIHPGYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDKQIVTSLLQAGHKGRVTGWGN
LKEMWTVNMNEVQPSVLQMVNLPLVERPICKASTGIRVTDNMFCAGYKPEEGKRGDACEG
DSGGPFVMKNPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIRKMVDRFG
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| BDBM50432209 |
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| n/a |
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| Name | BDBM50432209 |
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| Synonyms: | BIBR-1048 | BIBR-1048-BS-RS1 | DABIGATRAN ETEXILATE | Pradaxa |
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| Type | Small organic molecule |
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| Emp. Form. | C34H41N7O5 |
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| Mol. Mass. | 627.7332 |
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| SMILES | CCCCCCOC(=O)N=C(N)c1ccc(NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)OCC)c2ccccn2)cc1 |w:9.8| |
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| Structure | 
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