Reaction Details | |||
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Target | Free fatty acid receptor 4 | ||
Ligand | BDBM50207060 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_1629535 (CHEMBL3872161) | ||
EC50 | 5.6±n/a nM | ||
Citation | Adams, GL; Velazquez, F; Jayne, C; Shah, U; Miao, S; Ashley, ER; Madeira, M; Akiyama, TE; Di Salvo, J; Suzuki, T; Wang, N; Truong, Q; Gilbert, E; Zhou, D; Verras, A; Kirkland, M; Pachanski, M; Powles, M; Yin, W; Ujjainwalla, F; Venkatraman, S; Edmondson, SD Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with ACS Med Chem Lett8:96-101 (2017) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Free fatty acid receptor 4 | |||
Name: | Free fatty acid receptor 4 | ||
Synonyms: | FFAR4_MOUSE | Ffar4 | Free fatty acid receptor 4 | G-protein coupled receptor GT01 | Gpr120 | O3far1 | Omega-3 fatty acid receptor 1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 40828.60 | ||
Organism: | Mus musculus | ||
Description: | ChEMBL_1454435 | ||
Residue: | 361 | ||
Sequence: |
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BDBM50207060 | |||
n/a | |||
Name | BDBM50207060 | ||
Synonyms: | CHEMBL3952043 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H26FNO6 | ||
Mol. Mass. | 431.454 | ||
SMILES | CO[C@H]1C[C@@H](C1)Oc1cc(OC)c(F)c(n1)-c1ccc2O[C@@H](CCC(O)=O)CCc2c1 |r,wU:4.6,wD:21.23,2.1,(37.05,-1.75,;37.06,-3.29,;38.39,-4.05,;38.8,-5.54,;40.28,-5.13,;39.88,-3.65,;41.61,-5.9,;42.94,-5.12,;42.94,-3.58,;44.27,-2.81,;44.28,-1.27,;42.95,-.5,;45.61,-3.58,;46.94,-2.81,;45.6,-5.12,;44.28,-5.89,;46.93,-5.89,;46.93,-7.43,;48.27,-8.2,;49.6,-7.44,;50.93,-8.21,;52.28,-7.44,;53.61,-8.21,;54.95,-7.45,;56.28,-8.22,;56.28,-9.76,;57.62,-7.45,;52.29,-5.88,;50.94,-5.1,;49.6,-5.88,;48.26,-5.12,)| | ||
Structure |