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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2A | ||
| Ligand | BDBM50207147 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1630052 (CHEMBL3872758) | ||
| Ki | 0.350000±n/a nM | ||
| Citation |  Chen, XW; Sun, YY; Fu, L; Li, JQ Synthesis and pharmacological characterization of novel N-(trans-4-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)cyclohexyl)amides as potential multireceptor atypical antipsychotics. Eur J Med Chem123:332-353 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 2A | |||
| Name: | 5-hydroxytryptamine receptor 2A | ||
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A | ||
| Type: | undefined | ||
| Mol. Mass.: | 52607.65 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P28223 | ||
| Residue: | 471 | ||
| Sequence: |
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| BDBM50207147 | |||
| n/a | |||
| Name | BDBM50207147 | ||
| Synonyms: | CHEMBL3956720 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H32N4OS | ||
| Mol. Mass. | 412.591 | ||
| SMILES | O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)C1CC1 |r,wU:3.2,wD:6.6,(14.82,-26.62,;14.05,-25.29,;14.82,-23.96,;16.36,-23.96,;17.13,-22.62,;18.67,-22.62,;19.44,-23.96,;20.98,-23.96,;21.75,-22.62,;23.29,-22.62,;24.05,-21.29,;25.59,-21.29,;26.37,-22.62,;25.59,-23.96,;24.05,-23.96,;27.9,-22.62,;28.8,-23.87,;30.27,-23.39,;30.27,-21.85,;31.41,-20.82,;31.09,-19.32,;29.63,-18.85,;28.48,-19.88,;28.8,-21.38,;18.67,-25.29,;17.13,-25.29,;12.51,-25.29,;11.17,-26.05,;11.17,-24.51,)| | ||
| Structure | 
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