| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50207985 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1632268 (CHEMBL3874974) |
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| Ki | 13±n/a nM |
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| Citation |  Vullo, D; Del Prete, S; Nocentini, A; Osman, SM; AlOthman, Z; Capasso, C; Bozdag, M; Carta, F; Gratteri, P; Supuran, CT Dithiocarbamates effectively inhibit the฿-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa. Bioorg Med Chem25:1260-1265 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50207985 |
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| n/a |
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| Name | BDBM50207985 |
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| Synonyms: | CHEMBL3923883 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H19N2NaO2S2 |
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| Mol. Mass. | 298.401 |
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| SMILES | [Na+].CC(C)(C)OC(=O)NC1CCCN(C1)C([S-])=S |
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| Structure | 
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