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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Carbonic anhydrase 2 | ||
| Ligand | BDBM50067997 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1632268 (CHEMBL3874974) | ||
| Ki | 49±n/a nM | ||
| Citation |  Vullo, D; Del Prete, S; Nocentini, A; Osman, SM; AlOthman, Z; Capasso, C; Bozdag, M; Carta, F; Gratteri, P; Supuran, CT Dithiocarbamates effectively inhibit the฿-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa. Bioorg Med Chem25:1260-1265 (2017) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Carbonic anhydrase 2 | |||
| Name: | Carbonic anhydrase 2 | ||
| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 29250.71 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P00918 | ||
| Residue: | 260 | ||
| Sequence: |
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| BDBM50067997 | |||
| n/a | |||
| Name | BDBM50067997 | ||
| Synonyms: | CHEMBL3400801 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C8H13N2NaS2 | ||
| Mol. Mass. | 224.322 | ||
| SMILES | [Na+].[S-]C(=S)NC1CN2CCC1CC2 |(7.42,-3.05,;-.25,-3.45,;-.23,-2.28,;-1.25,-1.68,;1.05,-1.55,;2.32,-2.3,;2.3,-3.84,;3.64,-4.61,;4.97,-3.83,;4.97,-2.27,;3.64,-1.5,;3.11,-2.61,;4.14,-3.23,)| | ||
| Structure | 
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